WebApr 2, 2016 · Additionally, JCV is also the main causative factor for progressive multifocal leukoencephalopathy (PML), a frequent opportunistic infection in the CNS and a common complication seen in AIDS patients ... The cART-treated subjects are not able to purge the virus from their brains and show concomitant and persistent white matter abnormalities ... WebFeb 4, 2024 · This infection is called progressive multifocal leukoencephalopathy (PML). PML can be disabling, even fatal. PML can be disabling, even fatal. The role of immune-suppressing drugs
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WebProgressive multifocal leukoencephalopathy (PML) is a dreaded serious complication of immunotherapies. The drug with which it has been most frequently associated is natalizumab, a monoclonal antibody directed to alpha integrin that prevents the entry of lymphocytes to the central nervous system. ... (~10%) at particularly high risk for its ... WebMar 24, 2024 · The main option is to discontinue the use of any drugs that may be contributing to PML and seek supportive treatment. Some experts are currently investigating whether or not a drug called... the pitch uk
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