WebApr 7, 2002 · The reactions between cisplatin and DDTC, thiourea and thiosulfate were in vestigated in an unbu ff ered 0.10–0.05 mol dm ⫺ 3 chloride medium at 37 ⬚ C. All reactions f ollow the rate la w ... Webcisplatin, ddtc, counts, diethyldithiocarbamate, plasma, were, palladium, variability, day, rat, charge, analytical, acquisition, configuration, research, samples, mass, clinical, derivatization, qcs, analytically, stock, platinum, prepared, min, masshunter, working, accuracy, time, lloq, intra, determination, cpdpx, diamminedicholroplatinum, …
Cisplatin RxWiki
WebThis regimen of high-dose tamoxifen in combination with cisplatin can be safely administered. Serum tamoxifen levels comparable to concentrations required for enhancement of cisplatin sensitivity in vitro are clinically achievable with acceptable toxicity. The level of antitumor activity in nonsmall … WebCisplatin is one of the most potent anticancer agent used in the treatment of various solid tumors, however, its clinical use is limited due to severe adverse effects including nephrotoxicity. In this investigation cisplatin loaded poly (lactic-co-glycolic acid) (P d6 wavefront\u0027s
Application Note - Agilent Technologies
WebRats treated with cisplatin and then DDTC did not show a significant elevation of hearing threshold. DDTC-mediated protection was associated with higher levels of GSH (0.81 +/- 0.11 nmol/mg tissue), compared to 0.45 +/- 0.02 nmol/mg tissue following administration of cisplatin alone. WebSep 15, 2011 · Cisplatin or carboplatin and gold (III) as an internal standard were derivatized by N, N -diethyldithiocarbamate (DDTC). Pt (DDTC) 3+ and Au (DDTC) 2+ were monitored by the respective transitions of m / z 639.3–490.9 and 493.0–345.0, respectively. Each separation was completed within 9 min using a 3 μm particle ODS-column. WebDDTC also has application as a cleaning agent for cisplatin (e.g., for production equipment cleaning, spill cleanup). Destruction of cisplatin can be affected by the reaction of … d6 ward stepping hill