Citron homology

Author: nrgs

August undefined, 2024

WebSep 21, 2024 · Rom2, the guanine nucleotide exchange factor to Rho1, contains a C-terminal citron homology (CNH) domain of unknown function that is found in many other …

Human Vam6p promotes lysosome clustering and fusion in vivo

http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00036 WebBoth phosphorylation of Ser-348 and BLUS1 kinase activity are essential for activation of the H (+)-ATPase. blus1 mutants show lower stomatal conductance and CO2 assimilation than wild-type plants under decreased ambient CO2. Together, our analyses demonstrate that BLUS1 functions as a phototropin substrate and primary regulator of stomatal ... green fiber international inc

vps-39 CNH domain-containing protein;Vacuolar protein …

WebCitron homology (CNH) domain CRIB domain KELK-motif containing domain Myotonic dystrophy protein kinase, coiled coil PH-like domain superfamily Pleckstrin homology domain Protein kinase, ATP binding site Protein kinase C … WebMar 2, 2024 · This protein is localized to the plasma membrane by means of the citron homology domain, where the middle region binds to CK2, thus preventing it from phosphorylating PTEN. This activated PTEN downregulates phosphatidylinositol (3,4,5)-trisphosphate, an important driving factor of AKT signaling. Reduced AKT signaling leads … WebApr 15, 2013 · Citron-K is a multiple domain protein containing an N-terminal kinase domain, an internal coiled-coil (CC) domain with Rho/Rac interacting site, and a C … greenfiber insulation review

National Center for Biotechnology Information

MINK and TNIK Differentially Act on Rap2-Mediated Signal …

WebMay 26, 1998 · This region [“citron-homology” (CNH) domain] was identified as being homologous to the mouse Rho GTP /Rac GTP-binding protein, citron and to the C … WebCitron homology (CNH) domain CRIB domain KELK-motif containing domain Myotonic dystrophy protein kinase, coiled coil PH-like domain superfamily Pleckstrin homology … greenfiber recyclingWebHuman TNIK is a 1360-residue protein consisting of an N-terminal kinase domain, an intermediate domain, and a Cterminal domain conserved in the GCK family, which is termed the citron homology (CNH ... fluke tone and probe

"WebMost importantly, MRCKs, ROCKs, and CRIK contain a number of additional protein domains with distinct functions, including a small GTPase binding domain, a PH domain, a cysteine-rich domain, and a citron homology domain. It is this lack of motifs with known function that renders DMPK unique among its family members and in the AGC group as … " - Citron homology

Citron homology

WebJun 11, 2024 · The Ser/Thr kinase MAP4K4, like other GCKIV kinases, has N-terminal kinase and C-terminal citron homology (CNH) domains. MAP4K4 can activate c-Jun N … WebApr 16, 2004 · The CNH domain was originally found in citron that interacts with Rho and Rac . Subsequently, it was found in Rom2p, a GDP/GTP exchange factor for S. …

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WebHomology more Human Ortholog CIT, citron rho-interacting serine/threonine kinase Vertebrate Orthologs 3 Human Diseases more Diseases 1 with human CIT associations Mutations, Alleles, and Phenotypes less Phenotype Summary 26 phenotypes from 2 alleles in 2 genetic backgrounds 24 phenotype references Phenotype Overview WebMar 2, 2024 · Another important region identified was the citron homology domain located at the end of the protein. Through fluorescent imaging, it was discovered that this domain …

WebThe process of constructing SMART predicted (i) novel domain homologues in unexpected locations such as band 4.1-homologous domains in focal adhesion kinases; (ii) previously unknown domain families, including a citron-homology domain; (iii) putative functions of domain families after identification of additional family members, for example, a … WebJul 9, 2001 · Here, we report the identification of a novel human protein, hVam6p, that promotes lysosome clustering and fusion in vivo. Although hVam6p exhibits homology to the Saccharomyces cerevisiae vacuolar protein sorting gene product Vam6p/Vps39p, the presence of a citron homology (CNH) domain at the NH 2 terminus is unique to the …

WebNov 6, 1998 · Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron. We have identified a novel … WebSep 20, 2024 · The CNH domain plays an essential role as a stabilizer for the small GTPase Rho1, a key regulator of glucan biosynthesis. This work provides a model …

WebMar 2, 2024 · This protein is localized to the plasma membrane by means of the citron homology domain, where the middle region binds to CK2, thus preventing it from …

WebBased on sequence similarities a domain of homology has been identified near the N- or C-terminal end of the following proteins [1,2,3]: Citron Rho-interacting kinase … fluke tone and probe kitWebComparison Matrix. Gene Expression + Phenotype. Homozygotes for a null mutation are 20% smaller than wild-type and exhibit tremors, ataxia, and fatal seizures. Brains of … green fiber insulation vs fiberglass blow inWebNov 6, 1998 · We have identified a novel serine/threonine kinase belonging to the myotonic dystrophy kinase family. The kinase can be produced in at least two different isoforms: a approximately 240-kDa protein (Citron Rho-interacting kinase, CRIK), in which the kinase domain is followed by the sequence of Citron, a previously identified Rho/Rac binding … green fiber light cablesWebFeb 27, 2024 · C. elegans MRCK1 consists of an N-terminal CHB domain that mediates kinase domain dimerization, 28 followed by a region of predicted coiled-coil and C-terminal C1, pleckstrin homology (PH), and citron homology (CNH) domains of unknown structure and function (Figure 1 A). A Cdc42 and Rac-interactive binding (CRIB) motif is encoded … fluke toner tracer slow blink then fast blinkWebNational Center for Biotechnology Information green fiber sanctuary spec sheetWebNov 3, 2010 · GCK proteins are characterized by an N-terminal kinase domain and a C-terminal citron homology (CNH) domain separated by a variable region of lower sequence homology (Dan et al., 2001). MINK and TNIK specifically bind to Rap2 via their CNH domains ( Taira et al., 2004 ; Nonaka et al., 2008 ). green fiber insulation reviewWebMembers of this subfamily contain an N-terminal catalytic domain and a C-terminal citron homology (CNH) regulatory domain. MAP4K4 is also called Nck Interacting kinase (NIK). It facilitates the activation of the MAPKs, extracellular signal-regulated kinase (ERK) 1, ERK2, and c-Jun N-terminal kinase (JNK), by phosphorylating and activating MEKK1. fluke tl223 suregrip electrical test lead set